Chronic Wounds cam be Healed with Skin Replacement and Substitutes

Skin replacement and substitutes are talked mostly about, as a part of the treatment for chronic wounds. Apart from chronic wounds, this is an integral part of the cosmetic treatment spectrum treatment as well. Worry not, we will not complicate the matter that much by talking about both of the scenarios at once.

In this blog we will talk about the role of skin replacements and substitutes in the treatment of chronic wounds.

To talk about the treatment of chronic wounds, first, it is important to know that what exactly are chronic wounds, so we should start from there only.

Wounds are interruptions of the structural and functional integrity of the skin. Chronic wounds don’t often heal in an orderly and timely manner and regularly give out inflammation. Those with chronic wounds suffer a loss of function, recurrence of wound, and morbidity.

What are Chronic Wounds?

Chronic wounds comprise diabetic foot ulcers, pressure ulcers, and venous leg ulcers. These wounds might require precise interventions to restart the process of healing. Complete curing of chronic wounds is done with the reepithelization of epidermis and restoration of the dermis.

Chronic wound healing depends on appropriate blood flow and nutrition for ensuring growth of tissue, maintenance of a moist environment, infection control, and dead tissue removal for allowing space for new cells and for filling in the wound void.

Role of Skin Replacement and Substitutes in Healing of Chronic wounds

Chronic wounds do not always heal with the dressings and medications, and when that is the case the dead cells or tissues of the skin are replaced with skin substitutes to ensure that the healing process of the wounds fastens up.

Skin substitutes are a collection of a number of combinations of cellular and acellular components, derived from both animals and humans, for simulating the host to restore lost tissue and replace the wound with new and functional skin.

Cellular therapies, known as bioengineered cellular therapies offer skin cells to generate a number of growth factors, enzymes and cytokines that promote the regeneration of tissue.

Natural and artificial material, for instance collagen and polyglactin, might be employed for creating the extracellular matrix for ingrowth of the tissues. Acellular products offer an extracellular matrix bereft of cells and composed of a collagen substrate or further material into which cells can travel and initiate the regeneration of tissues.

Beyond just acting as a support, the extracellular matrix might also participate actively in stimulating the growth of the tissue. The broad category of skin substitutes might come good for stimulating healing of chronic wounds and reducing the medical burden these wounds generate.

It is due to the fact that skin replacement and substitutes come in handy in the healing of wounds and chronic wounds and also in cosmetic treatments happening all around the world, the demand for the same will continue to increase in the years to come.